; Zhan, H.; Cui, C.; Hideg, K.; Collier, R.J.; Hubbell, W.L. Organization of diphtheria toxin T domain in bilayers: A site-directed spin labeling study. Science 1996, 273, 810?12. Oh, K.J.; Zhan, H.; Cui, C.; Altenbach, C.; Hubbell, W.L.; Collier, R.J. Conformation of the diphtheria toxin t domain in membranes: A site-directed spin-labeling study of the TH8 helix and TL5 loop. Biochemistry 1999, 38, 10336?0343. Kachel, K.; Ren, J.H.; Collier, R.J.; London, E. Identifying transmembrane states and defining the membrane insertion boundaries of hydrophobic helices in membrane-inserted diphtheria toxin T domain. J. Biol. Chem. 1998, 273, 22950?2956. Senzel, L.; Gordon, M.; Blaustein, R.O.; Oh, K.J.; Collier, R.J.; Finkelstein, A. Topography of diphtheria toxin’s T domain in the open channel state. J. Gen. Physiol. 2000, 115, 421?34. Zhao, G.; London, E. Behavior of diphtheria toxin t domain containing substitutions that block normal membrane insertion at Pro345 and Leu307: Control of deep membrane insertion and coupling between deep insertion of hydrophobic subdomains. Biochemistry 2005, 44, 4488?498. Wang, Y.; Malenbaum, S.E.; Kachel, K.; Zhan, H.J.; Collier, R.J.; London, E. Identification of shallow and deep membrane-penetrating forms of diphtheria toxin T domain that happen to be regulated by protein concentration and bilayer width. J. Biol. Chem. 1997, 272, 25091?5098. Chenal, A.; Savarin, P.; Nizard, P.; Guillain, F.; Gillet, D.; Forge, V. Membrane protein insertion regulated by bringing electrostatic and hydrophobic interactions into play. A case study with all the translocation domain on the diphtheria toxin. J. Biol. Chem. 2002, 277, 43425?3432. Ladokhin, A.S.; Legmann, R.; Collier, R.J.; White, S.H. Reversible refolding in the diphtheria toxin T-domain on lipid membranes. Biochemistry 2004, 43, 7451?458. Palchevskyy, S.S.; Posokhov, Y.O.; Olivier, B.; Popot, J.L.; Pucci, B.; Ladokhin, A.S. Chaperoning of insertion of membrane proteins into lipid bilayers by hemifluorinated surfactants: Application to diphtheria toxin. Biochemistry 2006, 45, 2629?635. Montagner, C.; Perier, A.; Pichard, S.; Vernier, G.; Menez, A.; Gillet, D.; Forge, V.; Chenal, A. Behavior with the N-terminal helices of the diphtheria toxin T domain during the successive actions of membrane interaction. Biochemistry 2007, 46, 1878?887. Perier, A.; Chassaing, A.; Raffestin, S.; Pichard, S.; Masella, M.; Menez, A.; Forge, V.; Chenal, A.; Gillet, D. Concerted protonation of key histidines triggers membrane interaction from the diphtheria toxin T domain.1919022-57-3 Formula J.2059140-61-1 Price Biol.PMID:23546012 Chem. 2007, 282, 24239?4245. Posokhov, Y.O.; Rodnin, M.V.; Das, S.K.; Pucci, B.; Ladokhin, A.S. FCS study of the thermodynamics of membrane protein insertion into the lipid bilayer chaperoned by fluorinated surfactants. Biophys. J. 2008, 95, L54 56. Bennett, M.J.; Eisenberg, D. Refined structure of monomeric diphtheria toxin at 2.3 ?resolution. Protein Sci. 1994, 3, 1464?475.Toxins 2013,19. Weiss, M.S.; Blanke, S.R.; Collier, R.J.; Eisenberg, D. Structure of the isolated catalytic domain of diphtheria toxin. Biochemistry 1995, 34, 773?81. 20. Oh, K.J.; Senzel, L.; Collier, R.J.; Finkelstein, A. Translocation from the catalytic domain of diphtheria toxin across planar phospholipid bilayers by its personal T domain. Proc. Natl. Acad. Sci. USA 1999, 96, 8467?470. 21. Senzel, L.; Huynh, P.D.; Jakes, K.S.; Collier, R.J.; Finkelstein, A. The diphtheria toxin channel-forming T domain translocates its own NH2-terminal region across planar bilay.
